ApoE Alzheimer’s Disease Aβ-amyloid plaque morphology varies according to APOE isotype

BACKGROUND: The apolipoprotein E (APOE, gene; apoE, protein) ε4 allele is the most common identified genetic risk factor for typical late-onset sporadic Alzheimer’s disease (AD). Each APOE ε4 allele roughly triples the relative risk for AD compared to that of the reference allele, APOE ε3. METHODS:...

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Detalles Bibliográficos
Autores principales: Caesar, Ina, Nilsson, K Peter R, Hammarstrom, Per, Lindgren, Mikael, Prokop, Stefan, Heppner, Frank L, Schmeidler, James, Haroutunian, Vahram, Holtzman, David M, Hof, Patrick R, Gandy, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934766/
https://www.ncbi.nlm.nih.gov/pubmed/36798327
http://dx.doi.org/10.21203/rs.3.rs-2524641/v1

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