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Quantifying changes in the T cell receptor repertoire during thymic development

One of the feats of adaptive immunity is its ability to recognize foreign pathogens while sparing the self. During maturation in the thymus, T cells are selected through the binding properties of their antigen-specific T-cell receptor (TCR), through the elimination of both weakly (positive selection...

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Detalles Bibliográficos
Autores principales:	Camaglia, Francesco, Ryvkin, Arie, Greenstein, Erez, Reich-Zeliger, Shlomit, Chain, Benny, Mora, Thierry, Walczak, Aleksandra M, Friedman, Nir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934861/ https://www.ncbi.nlm.nih.gov/pubmed/36661220 http://dx.doi.org/10.7554/eLife.81622

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