Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome

Endometrial carcinosarcoma (ECS) is a rare, highly aggressive disease characterised by a biphasic growth of malignant epithelial (carcinomatous) and mesenchymal (sarcomatous) components. Clinically, it cannot be distinguished from endometrial carcinoma or uterine sarcoma. The definitive diagnosis ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Toro-Wills, María Fernanda, Álvarez-Londoño, Angelina, Hernández-Blanquisett, Abraham, Marquez, Fernando Salas, Martínez-Ávila, María Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934871/
https://www.ncbi.nlm.nih.gov/pubmed/36819811
http://dx.doi.org/10.3332/ecancer.2022.1472
Descripción
Sumario:Endometrial carcinosarcoma (ECS) is a rare, highly aggressive disease characterised by a biphasic growth of malignant epithelial (carcinomatous) and mesenchymal (sarcomatous) components. Clinically, it cannot be distinguished from endometrial carcinoma or uterine sarcoma. The definitive diagnosis can only be made based on histological examination and immunohistochemistry. To date, there aren’t standardised treatment protocols for its management. We report a case of a 73-year-old patient who presented postmenopausal abnormal uterine bleeding and was diagnosed with ECS. A non-conventional treatment approach was conducted with favourable oncological outcomes.

Ejemplares similares