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Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome
Endometrial carcinosarcoma (ECS) is a rare, highly aggressive disease characterised by a biphasic growth of malignant epithelial (carcinomatous) and mesenchymal (sarcomatous) components. Clinically, it cannot be distinguished from endometrial carcinoma or uterine sarcoma. The definitive diagnosis ca...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cancer Intelligence
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934871/ https://www.ncbi.nlm.nih.gov/pubmed/36819811 http://dx.doi.org/10.3332/ecancer.2022.1472 |
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author | Toro-Wills, María Fernanda Álvarez-Londoño, Angelina Hernández-Blanquisett, Abraham Marquez, Fernando Salas Martínez-Ávila, María Cristina |
author_facet | Toro-Wills, María Fernanda Álvarez-Londoño, Angelina Hernández-Blanquisett, Abraham Marquez, Fernando Salas Martínez-Ávila, María Cristina |
author_sort | Toro-Wills, María Fernanda |
collection | PubMed |
description | Endometrial carcinosarcoma (ECS) is a rare, highly aggressive disease characterised by a biphasic growth of malignant epithelial (carcinomatous) and mesenchymal (sarcomatous) components. Clinically, it cannot be distinguished from endometrial carcinoma or uterine sarcoma. The definitive diagnosis can only be made based on histological examination and immunohistochemistry. To date, there aren’t standardised treatment protocols for its management. We report a case of a 73-year-old patient who presented postmenopausal abnormal uterine bleeding and was diagnosed with ECS. A non-conventional treatment approach was conducted with favourable oncological outcomes. |
format | Online Article Text |
id | pubmed-9934871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cancer Intelligence |
record_format | MEDLINE/PubMed |
spelling | pubmed-99348712023-02-17 Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome Toro-Wills, María Fernanda Álvarez-Londoño, Angelina Hernández-Blanquisett, Abraham Marquez, Fernando Salas Martínez-Ávila, María Cristina Ecancermedicalscience Case Report Endometrial carcinosarcoma (ECS) is a rare, highly aggressive disease characterised by a biphasic growth of malignant epithelial (carcinomatous) and mesenchymal (sarcomatous) components. Clinically, it cannot be distinguished from endometrial carcinoma or uterine sarcoma. The definitive diagnosis can only be made based on histological examination and immunohistochemistry. To date, there aren’t standardised treatment protocols for its management. We report a case of a 73-year-old patient who presented postmenopausal abnormal uterine bleeding and was diagnosed with ECS. A non-conventional treatment approach was conducted with favourable oncological outcomes. Cancer Intelligence 2022-11-17 /pmc/articles/PMC9934871/ /pubmed/36819811 http://dx.doi.org/10.3332/ecancer.2022.1472 Text en © the authors; licensee ecancermedicalscience. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Toro-Wills, María Fernanda Álvarez-Londoño, Angelina Hernández-Blanquisett, Abraham Marquez, Fernando Salas Martínez-Ávila, María Cristina Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome |
title | Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome |
title_full | Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome |
title_fullStr | Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome |
title_full_unstemmed | Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome |
title_short | Endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome |
title_sort | endometrial carcinosarcoma: a poor prognosis debut with favourable therapeutic outcome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934871/ https://www.ncbi.nlm.nih.gov/pubmed/36819811 http://dx.doi.org/10.3332/ecancer.2022.1472 |
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