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Mobility and the spatial spread of sars-cov-2 in Belgium

We analyse and mutually compare time series of covid-19-related data and mobility data across Belgium’s 43 arrondissements (NUTS 3). In this way, we reach three conclusions. First, we could detect a decrease in mobility during high-incidence stages of the pandemic. This is expressed as a sizeable ch...

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Autores principales: Rollier, Michiel, Miranda, Gisele H.B., Vergeynst, Jenna, Meys, Joris, Alleman, Tijs W., Baetens, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934928/
https://www.ncbi.nlm.nih.gov/pubmed/36804448
http://dx.doi.org/10.1016/j.mbs.2022.108957
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author Rollier, Michiel
Miranda, Gisele H.B.
Vergeynst, Jenna
Meys, Joris
Alleman, Tijs W.
Baetens, Jan M.
author_facet Rollier, Michiel
Miranda, Gisele H.B.
Vergeynst, Jenna
Meys, Joris
Alleman, Tijs W.
Baetens, Jan M.
author_sort Rollier, Michiel
collection PubMed
description We analyse and mutually compare time series of covid-19-related data and mobility data across Belgium’s 43 arrondissements (NUTS 3). In this way, we reach three conclusions. First, we could detect a decrease in mobility during high-incidence stages of the pandemic. This is expressed as a sizeable change in the average amount of time spent outside one’s home arrondissement, investigated over five distinct periods, and in more detail using an inter-arrondissement “connectivity index” (CI). Second, we analyse spatio-temporal covid-19-related hospitalisation time series, after smoothing them using a generalise additive mixed model (GAMM). We confirm that some arrondissements are ahead of others and morphologically dissimilar to others, in terms of epidemiological progression. The tools used to quantify this are time-lagged cross-correlation (TLCC) and dynamic time warping (DTW), respectively. Third, we demonstrate that an arrondissement’s CI with one of the three identified first-outbreak arrondissements is correlated to a substantial local excess mortality some five to six weeks after the first outbreak. More generally, we couple results leading to the first and second conclusion, in order to demonstrate an overall correlation between CI values on the one hand, and TLCC and DTW values on the other. We conclude that there is a strong correlation between physical movement of people and viral spread in the early stage of the sars-cov-2 epidemic in Belgium, though its strength weakens as the virus spreads.
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spelling pubmed-99349282023-02-17 Mobility and the spatial spread of sars-cov-2 in Belgium Rollier, Michiel Miranda, Gisele H.B. Vergeynst, Jenna Meys, Joris Alleman, Tijs W. Baetens, Jan M. Math Biosci Original Research Article We analyse and mutually compare time series of covid-19-related data and mobility data across Belgium’s 43 arrondissements (NUTS 3). In this way, we reach three conclusions. First, we could detect a decrease in mobility during high-incidence stages of the pandemic. This is expressed as a sizeable change in the average amount of time spent outside one’s home arrondissement, investigated over five distinct periods, and in more detail using an inter-arrondissement “connectivity index” (CI). Second, we analyse spatio-temporal covid-19-related hospitalisation time series, after smoothing them using a generalise additive mixed model (GAMM). We confirm that some arrondissements are ahead of others and morphologically dissimilar to others, in terms of epidemiological progression. The tools used to quantify this are time-lagged cross-correlation (TLCC) and dynamic time warping (DTW), respectively. Third, we demonstrate that an arrondissement’s CI with one of the three identified first-outbreak arrondissements is correlated to a substantial local excess mortality some five to six weeks after the first outbreak. More generally, we couple results leading to the first and second conclusion, in order to demonstrate an overall correlation between CI values on the one hand, and TLCC and DTW values on the other. We conclude that there is a strong correlation between physical movement of people and viral spread in the early stage of the sars-cov-2 epidemic in Belgium, though its strength weakens as the virus spreads. Elsevier Inc. 2023-06 2023-02-17 /pmc/articles/PMC9934928/ /pubmed/36804448 http://dx.doi.org/10.1016/j.mbs.2022.108957 Text en © 2023 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Research Article
Rollier, Michiel
Miranda, Gisele H.B.
Vergeynst, Jenna
Meys, Joris
Alleman, Tijs W.
Baetens, Jan M.
Mobility and the spatial spread of sars-cov-2 in Belgium
title Mobility and the spatial spread of sars-cov-2 in Belgium
title_full Mobility and the spatial spread of sars-cov-2 in Belgium
title_fullStr Mobility and the spatial spread of sars-cov-2 in Belgium
title_full_unstemmed Mobility and the spatial spread of sars-cov-2 in Belgium
title_short Mobility and the spatial spread of sars-cov-2 in Belgium
title_sort mobility and the spatial spread of sars-cov-2 in belgium
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934928/
https://www.ncbi.nlm.nih.gov/pubmed/36804448
http://dx.doi.org/10.1016/j.mbs.2022.108957
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