Cargando…

NNMT Is an Immune-Related Prognostic Biomarker That Modulates the Tumor Microenvironment in Pan-Cancer

Emerging evidence has revealed the significant roles of nicotinamide n-methyltransferase (NNMT) in cancer initiation, development, and progression; however, a pan-cancer analysis of NNMT has not been conducted. In this study, we first thoroughly investigated the expression and prognostic significanc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Wenxiu, Zhu, Meng, Li, Xiaoming, Er, Limian, Li, Shengmian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934984/ https://www.ncbi.nlm.nih.gov/pubmed/36817086 http://dx.doi.org/10.1155/2023/9226712

Ejemplares similares

TTPAL promotes gastric tumorigenesis by directly targeting NNMT to activate PI3K/AKT signaling
por: Liu, Wenxiu, et al.
Publicado: (2021)

Expression profile and prognostic value of NNMT in patients with pancreatic cancer
por: Xu, Yong, et al.
Publicado: (2016)

Comparison between endoscopic mucosal resection with a cap and endoscopic submucosal dissection for rectal neuroendocrine tumors
por: Zheng, Xiuli, et al.
Publicado: (2022)

Vanillin downregulates NNMT and attenuates NNMT-related resistance to 5-fluorouracil via ROS-induced cell apoptosis in colorectal cancer cells
por: Li, Guoli, et al.
Publicado: (2021)

KNSTRN, a Poor Prognostic Biomarker, Affects the Tumor Immune Microenvironment and Immunotherapy Outcomes in Pan-Cancer
por: Zhang, Wanli, et al.
Publicado: (2023)

Identification of Biological Functions and Prognostic Value of NNMT in Oral Squamous Cell Carcinoma
por: Zhang, Weixian, et al.
Publicado: (2022)

Risk factors for lymph node metastasis and prognosis in colorectal neuroendocrine tumours
por: Zheng, Xiuli, et al.
Publicado: (2022)

Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review
por: Zheng, Xiuli, et al.
Publicado: (2023)

IMPDH1, a prognostic biomarker and immunotherapy target that correlates with tumor immune microenvironment in pan-cancer and hepatocellular carcinoma
por: Liu, Chengdong, et al.
Publicado: (2022)

CCDC137 Is a Prognostic Biomarker and Correlates With Immunosuppressive Tumor Microenvironment Based on Pan-Cancer Analysis
por: Guo, Lihao, et al.
Publicado: (2021)

Overexpression of NNMT in Glioma Aggravates Tumor Cell Progression: An Emerging Therapeutic Target
por: Sun, Wei, et al.
Publicado: (2022)

Identification of TIMP2 as a Prognostic Biomarker and Its Correlation with Tumor Immune Microenvironment: A Comprehensive Pan-Cancer Analysis
por: Wang, Dan-Dan, et al.
Publicado: (2022)

CD2 Is a Novel Immune-Related Prognostic Biomarker of Invasive Breast Carcinoma That Modulates the Tumor Microenvironment
por: Chen, Yanzhu, et al.
Publicado: (2021)

NNMT activation can contribute to the development of fatty liver disease by modulating the NAD(+) metabolism
por: Komatsu, Motoaki, et al.
Publicado: (2018)

Identify the Prognostic and Immune Profile of VSIR in the Tumor Microenvironment: A Pan-Cancer Analysis
por: Liu, Yuanyuan, et al.
Publicado: (2022)

Prognostic Values of METTL3 and Its Roles in Tumor Immune Microenvironment in Pan-Cancer
por: Guo, Yang, et al.
Publicado: (2022)

Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT) with Enhanced Activity
por: Gao, Yongzhi, et al.
Publicado: (2019)

Macrocyclic peptides as allosteric inhibitors of nicotinamide N-methyltransferase (NNMT)
por: van Haren, Matthijs J., et al.
Publicado: (2021)

A Systematic Immune and Prognostic Analysis of CD48 Interaction with Tumor Microenvironment in Pan-Cancer
por: He, Mingdong, et al.
Publicado: (2023)

HHLA2 Used as a Potential Prognostic and Immunological Biomarker and Correlated with Tumor Microenvironment in Pan-Cancer
por: Yang, Zeng, et al.
Publicado: (2022)

AP3S1 is a Novel Prognostic Biomarker and Correlated With an Immunosuppressive Tumor Microenvironment in Pan-Cancer
por: Wu, Gujie, et al.
Publicado: (2022)

KIF18B is a Prognostic Biomarker and Correlates with Immune Infiltrates in Pan-Cancer
por: Qiu, Meng-jun, et al.
Publicado: (2021)

FUCA2 Is a Prognostic Biomarker and Correlated With an Immunosuppressive Microenvironment in Pan-Cancer
por: Zhong, Anyuan, et al.
Publicado: (2021)

NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models
por: Layer, Moritz, et al.
Publicado: (2022)

Identification of prognostic biomarkers related to the tumor microenvironment in thyroid carcinoma
por: Du, Jun-wei, et al.
Publicado: (2021)

Proteomics reveals NNMT as a master metabolic regulator of cancer associated fibroblasts
por: Eckert, Mark A., et al.
Publicado: (2019)

DHRS7 is an immune-related prognostic biomarker of KIRC and pan-cancer
por: Tang, Sheng, et al.
Publicado: (2022)

High stromal nicotinamide N‐methyltransferase (NNMT) indicates poor prognosis in colorectal cancer
por: Song, Mengmeng, et al.
Publicado: (2020)

Pan-cancer analysis reveals NUP37 as a prognostic biomarker correlated with the immunosuppressive microenvironment in glioma
por: He, Ya, et al.
Publicado: (2022)

NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
por: Ulanovskaya, Olesya A., et al.
Publicado: (2013)

A pan-cancer analysis of the expression of gasdermin genes in tumors and their relationship with the immune microenvironment
por: Wang, Yuan-Yuan, et al.
Publicado: (2021)

BOP1 Used as a Novel Prognostic Marker and Correlated with Tumor Microenvironment in Pan-Cancer
por: Li, Wei, et al.
Publicado: (2021)

PTBPs: An immunomodulatory-related prognostic biomarker in pan-cancer
por: Chen, Chen, et al.
Publicado: (2022)

Identification of Tumor Microenvironment-Related Prognostic Biomarkers in Luminal Breast Cancer
por: Wang, Yanyan, et al.
Publicado: (2020)

Prognostic Implications of Pan-Cancer CMTM6 Expression and Its Relationship with the Immune Microenvironment
por: Zhao, Yanbin, et al.
Publicado: (2021)

Leptin Receptor Overlapping Transcript (LEPROT) Is Associated with the Tumor Microenvironment and a Prognostic Predictor in Pan-Cancer
por: Li, Bingsheng, et al.
Publicado: (2021)

Thrombospondin-1 is a prognostic biomarker and is correlated with tumor immune microenvironment in glioblastoma
por: Qi, Chunxiao, et al.
Publicado: (2021)

GABRP is a potential prognostic biomarker and correlated with immune infiltration and tumor microenvironment in pancreatic cancer
por: Yang, Yihui, et al.
Publicado: (2022)

CXCL10 is a Tumor Microenvironment and Immune Infiltration Related Prognostic Biomarker in Pancreatic Adenocarcinoma
por: Huang, Huimin, et al.
Publicado: (2021)

IRF7 as an Immune-Related Prognostic Biomarker and Associated with Tumor Microenvironment in Low-Grade Glioma
por: Peng, Shijun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kn2pj5rbjl1n15udpe039rv827