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Designing and Implementing “Living and Breathing” Clinical Trials: An Overview and Lessons Learned from the COVID-19 Pandemic

The practice of medicine is characterized by uncertainty, and the findings of randomized clinical trials (RCTs) are meant to help curb that uncertainty. Traditional RCTs, however, have many limitations. To overcome some of these limitations, new trial paradigms rooted in the origins of evidence-base...

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Detalles Bibliográficos
Autores principales: Horvat, Christopher M., King, Andrew J., Huang, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935272/
https://www.ncbi.nlm.nih.gov/pubmed/37704336
http://dx.doi.org/10.1016/j.ccc.2023.02.002