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Structures of transcription preinitiation complex engaged with the +1 nucleosome

The preinitiation complex (PIC) assembles on promoters of protein-coding genes to position RNA polymerase II (Pol II) for transcription initiation. Previous structural studies revealed the PIC on different promoters, but did not address how the PIC assembles within chromatin. In the yeast Saccharomy...

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Detalles Bibliográficos
Autores principales: Wang, Haibo, Schilbach, Sandra, Ninov, Momchil, Urlaub, Henning, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935396/
https://www.ncbi.nlm.nih.gov/pubmed/36411341
http://dx.doi.org/10.1038/s41594-022-00865-w