Remodeling of maternal mRNA through poly(A) tail orchestrates human oocyte-to-embryo transition

Poly(A)-tail-mediated post-transcriptional regulation of maternal mRNAs is vital in the oocyte-to-embryo transition (OET). Nothing is known about poly(A) tail dynamics during the human OET. Here, we show that poly(A) tail length and internal non-A residues are highly dynamic during the human OET, us...

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Detalles Bibliográficos
Autores principales: Liu, Yusheng, Zhao, Han, Shao, Fanghong, Zhang, Yiwei, Nie, Hu, Zhang, Jingye, Li, Cheng, Hou, Zhenzhen, Chen, Zi-Jiang, Wang, Jiaqiang, Zhou, Bing, Wu, Keliang, Lu, Falong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935398/
https://www.ncbi.nlm.nih.gov/pubmed/36646905
http://dx.doi.org/10.1038/s41594-022-00908-2

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