Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria

Approximately 20 TP53 retrogenes exist in the African and Asian elephant genomes (Loxodonta Africana, Elephas Maximus) in addition to a conserved TP53 gene that encodes a full-length protein. Elephant TP53-RETROGENE 9 (TP53-R9) encodes a p53 protein (p53-R9) that is truncated in the middle of the ca...

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Detalles Bibliográficos
Autores principales: Preston, Aidan J., Rogers, Aaron, Sharp, Miranda, Mitchell, Gareth, Toruno, Cristhian, Barney, Brayden B., Donovan, Lauren N., Bly, Journey, Kennington, Ryan, Payne, Emily, Iovino, Anthony, Furukawa, Gabriela, Robinson, Rosann, Shamloo, Bahar, Buccilli, Matthew, Anders, Rachel, Eckstein, Sarah, Fedak, Elizabeth A., Wright, Tanner, Maley, Carlo C., Kiso, Wendy K., Schmitt, Dennis, Malkin, David, Schiffman, Joshua D., Abegglen, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935553/
https://www.ncbi.nlm.nih.gov/pubmed/36797268
http://dx.doi.org/10.1038/s41420-023-01348-7

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