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Development and clinical evaluation of a CRISPR/Cas13a-based diagnostic test to detect Mycobacterium tuberculosis in clinical specimens

OBJECTIVE: Tuberculosis diagnosis requires rapid, simple and highly sensitive methods. Clustered regularly interspaced short palindromic repeats (CRISPRs) and associated protein (Cas) systems are increasingly being used for clinical diagnostic applications, due to their high flexibility, sensitivity...

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Detalles Bibliográficos
Autores principales:	Ren, Weicong, Zhou, You, Li, Haoran, Shang, Yuanyuan, Zhang, Xuxia, Yuan, Jinfeng, Li, Shanshan, Li, Chuanyou, Pang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935578/ https://www.ncbi.nlm.nih.gov/pubmed/36819015 http://dx.doi.org/10.3389/fmicb.2023.1117085

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