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Optimized protocol for MALDI MSI of N-glycans using an on-tissue digestion in fresh frozen tissue sections
Glycans play an important role in biology with multiple cellular functions ranging from cell signaling, mobility and growth to protein folding and localization. The N-glycosylation state within a tissue has been found to vary greatly between healthy and diseased patients and has proven to have an im...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935634/ https://www.ncbi.nlm.nih.gov/pubmed/36797298 http://dx.doi.org/10.1038/s41598-023-29560-6 |