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Optimized protocol for MALDI MSI of N-glycans using an on-tissue digestion in fresh frozen tissue sections

Glycans play an important role in biology with multiple cellular functions ranging from cell signaling, mobility and growth to protein folding and localization. The N-glycosylation state within a tissue has been found to vary greatly between healthy and diseased patients and has proven to have an im...

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Detalles Bibliográficos
Autores principales: Grgic, Andrej, Krestensen, Kasper K., Heeren, Ron M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935634/
https://www.ncbi.nlm.nih.gov/pubmed/36797298
http://dx.doi.org/10.1038/s41598-023-29560-6

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