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Prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram

Hypertensive intracerebral hemorrhage (HICH) is the most common type of spontaneous intracerebral hemorrhage in China which is associated with high mortality and disability. We sought to develop and validate a noncontrast computed tomography (NCCT)-based nomogram model to achieve short-term prognost...

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Autores principales: Wang, Jing, Zhou, Lu, Chen, Yuanyuan, Zhou, Hongli, Tan, Yuanxin, Zhong, Weijia, Zhou, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935706/
https://www.ncbi.nlm.nih.gov/pubmed/36816560
http://dx.doi.org/10.3389/fneur.2023.1053846
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author Wang, Jing
Zhou, Lu
Chen, Yuanyuan
Zhou, Hongli
Tan, Yuanxin
Zhong, Weijia
Zhou, Zhiming
author_facet Wang, Jing
Zhou, Lu
Chen, Yuanyuan
Zhou, Hongli
Tan, Yuanxin
Zhong, Weijia
Zhou, Zhiming
author_sort Wang, Jing
collection PubMed
description Hypertensive intracerebral hemorrhage (HICH) is the most common type of spontaneous intracerebral hemorrhage in China which is associated with high mortality and disability. We sought to develop and validate a noncontrast computed tomography (NCCT)-based nomogram model to achieve short-term prognostic prediction for patients with HICH. We retrospectively studied 292 patients with HICH from two medical centers, and they were divided into training (n = 151), validation (n = 66), and testing cohorts (n = 75). Based on radiomics, univariate and multivariate, and logistic regression analyses, four models (black hole sign, clinical, radiomics score, and combined models) were established to predict the prognosis of patients with HICH 30 days after the onset. The results suggested that the combined model had the best predictive performance with the area under the receiver operating characteristic curve (AUC) of 0.821, 0.816, and 0.815 in the training, validation, and testing cohorts, respectively. In addition, a radiomics-clinical (R-C) nomogram was visualized. A calibration curve analysis showed that the R-C nomogram had satisfactory calibration in the three cohorts. A decision curve analysis demonstrated that the R-C nomogram was clinically valuable. Our results suggest that the R-C nomogram can accurately and reliably predict the short-term prognosis of patients with HICH and provide a useful evaluation for making individualized treatment plans.
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spelling pubmed-99357062023-02-18 Prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram Wang, Jing Zhou, Lu Chen, Yuanyuan Zhou, Hongli Tan, Yuanxin Zhong, Weijia Zhou, Zhiming Front Neurol Neurology Hypertensive intracerebral hemorrhage (HICH) is the most common type of spontaneous intracerebral hemorrhage in China which is associated with high mortality and disability. We sought to develop and validate a noncontrast computed tomography (NCCT)-based nomogram model to achieve short-term prognostic prediction for patients with HICH. We retrospectively studied 292 patients with HICH from two medical centers, and they were divided into training (n = 151), validation (n = 66), and testing cohorts (n = 75). Based on radiomics, univariate and multivariate, and logistic regression analyses, four models (black hole sign, clinical, radiomics score, and combined models) were established to predict the prognosis of patients with HICH 30 days after the onset. The results suggested that the combined model had the best predictive performance with the area under the receiver operating characteristic curve (AUC) of 0.821, 0.816, and 0.815 in the training, validation, and testing cohorts, respectively. In addition, a radiomics-clinical (R-C) nomogram was visualized. A calibration curve analysis showed that the R-C nomogram had satisfactory calibration in the three cohorts. A decision curve analysis demonstrated that the R-C nomogram was clinically valuable. Our results suggest that the R-C nomogram can accurately and reliably predict the short-term prognosis of patients with HICH and provide a useful evaluation for making individualized treatment plans. Frontiers Media S.A. 2023-02-03 /pmc/articles/PMC9935706/ /pubmed/36816560 http://dx.doi.org/10.3389/fneur.2023.1053846 Text en Copyright © 2023 Wang, Zhou, Chen, Zhou, Tan, Zhong and Zhou. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Wang, Jing
Zhou, Lu
Chen, Yuanyuan
Zhou, Hongli
Tan, Yuanxin
Zhong, Weijia
Zhou, Zhiming
Prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram
title Prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram
title_full Prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram
title_fullStr Prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram
title_full_unstemmed Prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram
title_short Prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram
title_sort prediction of short-term prognosis of patients with hypertensive intracerebral hemorrhage by radiomic-clinical nomogram
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935706/
https://www.ncbi.nlm.nih.gov/pubmed/36816560
http://dx.doi.org/10.3389/fneur.2023.1053846
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