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Clinical correlates of R1 relaxometry and magnetic susceptibility changes in multiple sclerosis: a multi-parameter quantitative MRI study of brain iron and myelin

OBJECTIVES: The clinical impact of brain microstructural abnormalities in multiple sclerosis (MS) remains elusive. We aimed to characterize the topography of longitudinal relaxation rate (R1) and quantitative susceptibility (χ) changes, as indices of iron and myelin, together with brain atrophy, and...

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Detalles Bibliográficos
Autores principales:	Pontillo, Giuseppe, Petracca, Maria, Monti, Serena, Quarantelli, Mario, Lanzillo, Roberta, Costabile, Teresa, Carotenuto, Antonio, Tortora, Fabio, Elefante, Andrea, Morra, Vincenzo Brescia, Brunetti, Arturo, Palma, Giuseppe, Cocozza, Sirio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Neuro
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935712/ https://www.ncbi.nlm.nih.gov/pubmed/36241917 http://dx.doi.org/10.1007/s00330-022-09154-y

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