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Glutamine is a substrate for glycosylation and CA19-9 biosynthesis through hexosamine biosynthetic pathway in pancreatic cancer

BACKGROUND: Carbohydrate antigen 19–9 (CA19-9) is the most widely used biomarker for pancreatic cancer. Since CA19-9 closely correlates with patient outcome and tumor stage in pancreatic cancer, the deciphering of CA19-9 biosynthesis provides a potential clue for treatment. METHODS: Concentration of...

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Detalles Bibliográficos
Autores principales: Liu, Chen, Deng, Shengming, Xiao, Zhiwen, Lu, Renquan, Cheng, He, Feng, Jingjing, Shen, Xuxia, Ni, Quanxing, Wu, Weiding, Yu, Xianjun, Luo, Guopei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935803/
https://www.ncbi.nlm.nih.gov/pubmed/36797531
http://dx.doi.org/10.1007/s12672-023-00628-z