Cargando…

Molecular Modeling Identification of Key Secondary Metabolites from Xylopia aethiopica as Promising Therapeutics Targeting Essential Measles Viral Proteins

This study computationally screened three key compounds (vanillin (VAN), oxophoebine (OPB), and dihydrochalcone (DHC)) derived from Xylopia aethiopica (Guinea pepper), a medicinal plant with known antiviral activity, against key druggable measles virus (MV) proteins (fusion protein (FUP), haemagglut...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oloche, Jeremiah John, Oluremi, Bolaji Bosede, Aruwa, Christiana Eleojo, Sabiu, Saheed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935805/ https://www.ncbi.nlm.nih.gov/pubmed/36818222 http://dx.doi.org/10.1155/2023/1575358

Ejemplares similares

Characterization of the antiproliferative activity of Xylopia aethiopica
por: Choumessi, Aphrodite T, et al.
Publicado: (2012)

Poultry gut health – microbiome functions, environmental impacts, microbiome engineering and advancements in characterization technologies
por: Aruwa, Christiana Eleojo, et al.
Publicado: (2021)

Cheminformatics Bioprospection of Broad Spectrum Plant Secondary Metabolites Targeting the Spike Proteins of Omicron Variant and Wild-Type SARS-CoV-2
por: Aribisala, Jamiu Olaseni, et al.
Publicado: (2022)

An Appraisal of Antidotes’ Effectiveness: Evidence of the Use of Phyto-Antidotes and Biotechnological Advancements
por: Aruwa, Christiana Eleojo, et al.
Publicado: (2020)

Composition and cytotoxic activity of essential oils from Xylopia aethiopica (Dunal) A. Rich, Xylopia parviflora (A. Rich) Benth.) and Monodora myristica (Gaertn) growing in Chad and Cameroon
por: Bakarnga-Via, Issakou, et al.
Publicado: (2014)

Extract of Xylopia aethiopica and its kaurene diterpene, xylopic acid, improve learning and memory in mice
por: Koomson, Awo Efua, et al.
Publicado: (2022)

Comparative Biochemical Evaluation of the Proximate, Mineral, and Phytochemical Constituents of Xylopia aethiopica Whole Fruit, Seed, and Pericarp
por: Fategbe, Mojisola Adebimpe, et al.
Publicado: (2021)

Behavioural and biochemical indications of the antidepressant activities of essential oils from Monodora myristica (Gaertn) seed and Xylopia aethiopica (Dunal) fruit in rats
por: Ekeanyanwu, Raphael Chukwuma, et al.
Publicado: (2021)

Network Pharmacology- and Molecular Dynamics Simulation-Based Bioprospection of Aspalathus linearis for Type-2 Diabetes Care
por: Akoonjee, Ayesha, et al.
Publicado: (2022)

Toxicity study of ethanolic stem bark extract of Xylopia aethiopica on fertility indices of male rats: An experimental study
por: Ehigiator, Ben Enoluomen, et al.
Publicado: (2020)

Molecular docking and ADMET studies of Allium cepa, Azadirachta indica and Xylopia aethiopica isolates as potential anti-viral drugs for Covid-19
por: Adegbola, Peter Ifeoluwa, et al.
Publicado: (2021)

Xylopia aethiopica Seeds from Two Countries in West Africa Exhibit Differences in Their Proteomes, Mineral Content and Bioactive Phytochemical Composition
por: Yin, Xiaojian, et al.
Publicado: (2019)

Antibiofilm and Enzyme Inhibitory Potentials of Two Annonaceous Food Spices, African Pepper (Xylopia aethiopica) and African Nutmeg (Monodora myristica)
por: Tamfu, Alfred Ngenge, et al.
Publicado: (2020)

Xylopia aethiopica ethanol seed extract suppresses Cadmium chloride-induced ovary and gonadotropins toxicity in adult female Wistar rats
por: Godam, Elvis T, et al.
Publicado: (2021)

Analgesic effects of an ethanol extract of the fruits of Xylopia aethiopica (Dunal) A. Rich (Annonaceae) and the major constituent, xylopic acid in murine models
por: Woode, Eric, et al.
Publicado: (2012)

Anti-allodynic and Anti-hyperalgesic effects of an ethanolic extract and xylopic acid from the fruits of Xylopia aethiopica in murine models of neuropathic pain
por: Ameyaw, Elvis O., et al.
Publicado: (2014)

Comparative Effects of Some Medicinal Plants: Anacardium occidentale, Eucalyptus globulus, Psidium guajava, and Xylopia aethiopica Extracts in Alloxan-Induced Diabetic Male Wistar Albino Rats
por: Okpashi, Victor Eshu, et al.
Publicado: (2014)

Prospects of nanodentistry for the diagnosis and treatment of maxillofacial pathologies and cancers
por: Adeola, Henry A., et al.
Publicado: (2020)

Anti-Th17 and anti-Th2 responses effects of hydro-ethanolic extracts of Aframomum melegueta, Khaya senegalensis and Xylopia aethiopica in hyperreactive onchocerciasis individuals’ peripheral blood mononuclear cells
por: Katawa, Gnatoulma, et al.
Publicado: (2022)

Genome diversity of Leishmania aethiopica
por: Hadermann, Amber, et al.
Publicado: (2023)

Diet of Broilers with Essential Oil from Citrus sinensis and Xylopia aromatica Fruits
por: Christofoli, Marcela, et al.
Publicado: (2023)

Cutaneous Leishmaniasis Due to Leishmania aethiopica
por: van Henten, Saskia, et al.
Publicado: (2019)

Redox Impact on Bacterial Macromolecule: A Promising Avenue for Discovery and Development of Novel Antibacterials
por: Aribisala, Jamiu Olaseni, et al.
Publicado: (2022)

Cytotoxic Alkaloids from the Stem of Xylopia laevigata
por: Menezes, Leociley R. A., et al.
Publicado: (2016)

Evaluation of the Anti-Inflammatory and Antinociceptive Effects of the Essential Oil from Leaves of Xylopia laevigata in Experimental Models
por: Queiroz, João Carlos C., et al.
Publicado: (2014)

Identification of Flavonoid C-Glycosides as Promising Antidiabetics Targeting Protein Tyrosine Phosphatase 1B
por: Rampadarath, Athika, et al.
Publicado: (2022)

Cutaneous leishmaniasis due to Leishmania aethiopica: A therapeutic challenge
por: Mengeot, Laura, et al.
Publicado: (2021)

Multilocus microsatellite signature and identification of specific molecular markers for Leishmania aethiopica
por: Kebede, Nigatu, et al.
Publicado: (2013)

Treatment of Cutaneous Leishmaniasis Caused by Leishmania aethiopica: A Systematic Review
por: van Griensven, Johan, et al.
Publicado: (2016)

Phytochemical Profile, Antioxidant Potential and Toxicity Evaluation of the Essential Oils from Duguetia and Xylopia Species (Annonaceae) from the Brazilian Amazon
por: Cascaes, Márcia Moraes, et al.
Publicado: (2022)

The neuroprotective effect of Xylopia parviflora against aluminum chloride-induced neurotoxicity in rats
por: Kemadjou Dibacto, Ruth Edwige, et al.
Publicado: (2022)

Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)
por: Araújo, Fernanda de Paula, et al.
Publicado: (2019)

In Vitro and in Vivo Antitumor Effect of Trachylobane-360, a Diterpene from Xylopia langsdorffiana
por: Pita, João Carlos Lima Rodrigues, et al.
Publicado: (2012)

KINETICS OF MODULATORY ROLE OF Cyperus esculentus L. ON THE SPECIFIC ACTIVITY OF KEY CARBOHYDRATE METABOLIZING ENZYMES
por: Sabiu, Saheed, et al.
Publicado: (2017)

The Genetic Relationship between Leishmania aethiopica and Leishmania tropica Revealed by Comparing Microsatellite Profiles
por: Krayter, Lena, et al.
Publicado: (2015)

Essential oil from Xylopia frutescens Aubl. reduces cytosolic calcium levels on guinea pig ileum: mechanism underlying its spasmolytic potential
por: Souza, Iara Leão Luna de, et al.
Publicado: (2015)

Molecular modelling identification of phytocompounds from selected African botanicals as promising therapeutics against druggable human host cell targets of SARS-CoV-2
por: Uhomoibhi, John Omo-Osagie, et al.
Publicado: (2022)

Xyloplains A–F, six new guaiane-type sesquiterpenoid dimers from Xylopia vielana
por: Xie, Yang-Guo, et al.
Publicado: (2018)

Rhinophyma-Like Cutaneous Leishmaniasis due to Leishmania aethiopica Treated Successfully with Liposomal Amphotericin B
por: Kirchberger, Michael Constantin, et al.
Publicado: (2019)

Feeding behavior and activity of Phlebotomus pedifer and potential reservoir hosts of Leishmania aethiopica in southwestern Ethiopia
por: Pareyn, Myrthe, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hvsdj3mm2kmrstn33u9hailkuh