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Ischemic stroke protected by ISO-1 inhibition of apoptosis via mitochondrial pathway

Macrophage migration inhibitory factor (MIF) is an immune mediator associated with inflammation, which is upregulated after ischemia in brain tissue. ISO-1 is a potent inhibitor of MIF tautomerase and can protect neurons by reducing the permeability of blood brain barrier (BBB). In this study, we in...

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Detalles Bibliográficos
Autores principales: Ji, Wanli, Ren, Yaoxin, Wei, Xiaolian, Ding, Xiangxiang, Dong, Yihan, Yuan, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935850/
https://www.ncbi.nlm.nih.gov/pubmed/36797398
http://dx.doi.org/10.1038/s41598-023-29907-z