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Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility

Identification of protein quantitative trait loci (pQTL) helps understand the underlying mechanisms of diseases and discover promising targets for pharmacological intervention. For most important class of drug targets, genetic evidence needs to be generalizable to diverse populations. Given that the...

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Detalles Bibliográficos
Autores principales: Xu, Fengzhe, Yu, Evan Yi-Wen, Cai, Xue, Yue, Liang, Jing, Li-peng, Liang, Xinxiu, Fu, Yuanqing, Miao, Zelei, Yang, Min, Shuai, Menglei, Gou, Wanglong, Xiao, Congmei, Xue, Zhangzhi, Xie, Yuting, Li, Sainan, Lu, Sha, Shi, Meiqi, Wang, Xuhong, Hu, Wensheng, Langenberg, Claudia, Yang, Jian, Chen, Yu-ming, Guo, Tiannan, Zheng, Ju-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935862/
https://www.ncbi.nlm.nih.gov/pubmed/36797296
http://dx.doi.org/10.1038/s41467-023-36491-3