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Nicotine rebalances NAD(+) homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity
Imbalances in NAD(+) homeostasis have been linked to aging and various diseases. Nicotine, a metabolite of the NAD(+) metabolic pathway, has been found to possess anti-inflammatory and neuroprotective properties, yet the underlying molecular mechanisms remained unknown. Here we find that, independen...
Autores principales: | Yang, Liang, Shen, Junfeng, Liu, Chunhua, Kuang, Zhonghua, Tang, Yong, Qian, Zhengjiang, Guan, Min, Yang, Yongfeng, Zhan, Yang, Li, Nan, Li, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935903/ https://www.ncbi.nlm.nih.gov/pubmed/36797299 http://dx.doi.org/10.1038/s41467-023-36543-8 |
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