Cargando…
Impact of age for overall survival in head and neck sarcoma
The purpose to the present study is to research the association between age at surgery and survival outcomes of patients with sarcoma in head and neck. Twenty-six patients with head and neck sarcoma who underwent by surgery from 2003 to 2017 were enrolled in the present observation study. Patients w...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935989/ https://www.ncbi.nlm.nih.gov/pubmed/36800630 http://dx.doi.org/10.1097/MD.0000000000032966 |
_version_ | 1784890137032785920 |
---|---|
author | Suzuki, Hidenori Takano, Gaku Tsukushi, Satoshi Ando, Masashi Yatabe, Yasushi Kodaira, Takeshi Nishikawa, Daisuke Beppu, Shintaro Hasegawa, Yasuhisa Hanai, Nobuhiro |
author_facet | Suzuki, Hidenori Takano, Gaku Tsukushi, Satoshi Ando, Masashi Yatabe, Yasushi Kodaira, Takeshi Nishikawa, Daisuke Beppu, Shintaro Hasegawa, Yasuhisa Hanai, Nobuhiro |
author_sort | Suzuki, Hidenori |
collection | PubMed |
description | The purpose to the present study is to research the association between age at surgery and survival outcomes of patients with sarcoma in head and neck. Twenty-six patients with head and neck sarcoma who underwent by surgery from 2003 to 2017 were enrolled in the present observation study. Patients who did not undergo chemotherapy were significantly older age at surgery by Mann–Whitney U test. Fifty-five was the cutoff age that predicted death by receiver operating curve analysis. Shorter survival rates of overall, disease-specific, local recurrence-free and disease-free were associated with older age by log-rank test. Age (≥55 years/<55 years) was correlated with shorter overall survival by multivariate analysis of Cox’s proportional hazards model adjusting with chemotherapy (absence/presence). In conclusion, older age predicts worse overall survival in head and neck sarcoma. |
format | Online Article Text |
id | pubmed-9935989 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-99359892023-02-18 Impact of age for overall survival in head and neck sarcoma Suzuki, Hidenori Takano, Gaku Tsukushi, Satoshi Ando, Masashi Yatabe, Yasushi Kodaira, Takeshi Nishikawa, Daisuke Beppu, Shintaro Hasegawa, Yasuhisa Hanai, Nobuhiro Medicine (Baltimore) 5700 The purpose to the present study is to research the association between age at surgery and survival outcomes of patients with sarcoma in head and neck. Twenty-six patients with head and neck sarcoma who underwent by surgery from 2003 to 2017 were enrolled in the present observation study. Patients who did not undergo chemotherapy were significantly older age at surgery by Mann–Whitney U test. Fifty-five was the cutoff age that predicted death by receiver operating curve analysis. Shorter survival rates of overall, disease-specific, local recurrence-free and disease-free were associated with older age by log-rank test. Age (≥55 years/<55 years) was correlated with shorter overall survival by multivariate analysis of Cox’s proportional hazards model adjusting with chemotherapy (absence/presence). In conclusion, older age predicts worse overall survival in head and neck sarcoma. Lippincott Williams & Wilkins 2023-02-17 /pmc/articles/PMC9935989/ /pubmed/36800630 http://dx.doi.org/10.1097/MD.0000000000032966 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | 5700 Suzuki, Hidenori Takano, Gaku Tsukushi, Satoshi Ando, Masashi Yatabe, Yasushi Kodaira, Takeshi Nishikawa, Daisuke Beppu, Shintaro Hasegawa, Yasuhisa Hanai, Nobuhiro Impact of age for overall survival in head and neck sarcoma |
title | Impact of age for overall survival in head and neck sarcoma |
title_full | Impact of age for overall survival in head and neck sarcoma |
title_fullStr | Impact of age for overall survival in head and neck sarcoma |
title_full_unstemmed | Impact of age for overall survival in head and neck sarcoma |
title_short | Impact of age for overall survival in head and neck sarcoma |
title_sort | impact of age for overall survival in head and neck sarcoma |
topic | 5700 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935989/ https://www.ncbi.nlm.nih.gov/pubmed/36800630 http://dx.doi.org/10.1097/MD.0000000000032966 |
work_keys_str_mv | AT suzukihidenori impactofageforoverallsurvivalinheadandnecksarcoma AT takanogaku impactofageforoverallsurvivalinheadandnecksarcoma AT tsukushisatoshi impactofageforoverallsurvivalinheadandnecksarcoma AT andomasashi impactofageforoverallsurvivalinheadandnecksarcoma AT yatabeyasushi impactofageforoverallsurvivalinheadandnecksarcoma AT kodairatakeshi impactofageforoverallsurvivalinheadandnecksarcoma AT nishikawadaisuke impactofageforoverallsurvivalinheadandnecksarcoma AT beppushintaro impactofageforoverallsurvivalinheadandnecksarcoma AT hasegawayasuhisa impactofageforoverallsurvivalinheadandnecksarcoma AT hanainobuhiro impactofageforoverallsurvivalinheadandnecksarcoma |