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Impact of age for overall survival in head and neck sarcoma

The purpose to the present study is to research the association between age at surgery and survival outcomes of patients with sarcoma in head and neck. Twenty-six patients with head and neck sarcoma who underwent by surgery from 2003 to 2017 were enrolled in the present observation study. Patients w...

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Autores principales: Suzuki, Hidenori, Takano, Gaku, Tsukushi, Satoshi, Ando, Masashi, Yatabe, Yasushi, Kodaira, Takeshi, Nishikawa, Daisuke, Beppu, Shintaro, Hasegawa, Yasuhisa, Hanai, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935989/
https://www.ncbi.nlm.nih.gov/pubmed/36800630
http://dx.doi.org/10.1097/MD.0000000000032966
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author Suzuki, Hidenori
Takano, Gaku
Tsukushi, Satoshi
Ando, Masashi
Yatabe, Yasushi
Kodaira, Takeshi
Nishikawa, Daisuke
Beppu, Shintaro
Hasegawa, Yasuhisa
Hanai, Nobuhiro
author_facet Suzuki, Hidenori
Takano, Gaku
Tsukushi, Satoshi
Ando, Masashi
Yatabe, Yasushi
Kodaira, Takeshi
Nishikawa, Daisuke
Beppu, Shintaro
Hasegawa, Yasuhisa
Hanai, Nobuhiro
author_sort Suzuki, Hidenori
collection PubMed
description The purpose to the present study is to research the association between age at surgery and survival outcomes of patients with sarcoma in head and neck. Twenty-six patients with head and neck sarcoma who underwent by surgery from 2003 to 2017 were enrolled in the present observation study. Patients who did not undergo chemotherapy were significantly older age at surgery by Mann–Whitney U test. Fifty-five was the cutoff age that predicted death by receiver operating curve analysis. Shorter survival rates of overall, disease-specific, local recurrence-free and disease-free were associated with older age by log-rank test. Age (≥55 years/<55 years) was correlated with shorter overall survival by multivariate analysis of Cox’s proportional hazards model adjusting with chemotherapy (absence/presence). In conclusion, older age predicts worse overall survival in head and neck sarcoma.
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spelling pubmed-99359892023-02-18 Impact of age for overall survival in head and neck sarcoma Suzuki, Hidenori Takano, Gaku Tsukushi, Satoshi Ando, Masashi Yatabe, Yasushi Kodaira, Takeshi Nishikawa, Daisuke Beppu, Shintaro Hasegawa, Yasuhisa Hanai, Nobuhiro Medicine (Baltimore) 5700 The purpose to the present study is to research the association between age at surgery and survival outcomes of patients with sarcoma in head and neck. Twenty-six patients with head and neck sarcoma who underwent by surgery from 2003 to 2017 were enrolled in the present observation study. Patients who did not undergo chemotherapy were significantly older age at surgery by Mann–Whitney U test. Fifty-five was the cutoff age that predicted death by receiver operating curve analysis. Shorter survival rates of overall, disease-specific, local recurrence-free and disease-free were associated with older age by log-rank test. Age (≥55 years/<55 years) was correlated with shorter overall survival by multivariate analysis of Cox’s proportional hazards model adjusting with chemotherapy (absence/presence). In conclusion, older age predicts worse overall survival in head and neck sarcoma. Lippincott Williams & Wilkins 2023-02-17 /pmc/articles/PMC9935989/ /pubmed/36800630 http://dx.doi.org/10.1097/MD.0000000000032966 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 5700
Suzuki, Hidenori
Takano, Gaku
Tsukushi, Satoshi
Ando, Masashi
Yatabe, Yasushi
Kodaira, Takeshi
Nishikawa, Daisuke
Beppu, Shintaro
Hasegawa, Yasuhisa
Hanai, Nobuhiro
Impact of age for overall survival in head and neck sarcoma
title Impact of age for overall survival in head and neck sarcoma
title_full Impact of age for overall survival in head and neck sarcoma
title_fullStr Impact of age for overall survival in head and neck sarcoma
title_full_unstemmed Impact of age for overall survival in head and neck sarcoma
title_short Impact of age for overall survival in head and neck sarcoma
title_sort impact of age for overall survival in head and neck sarcoma
topic 5700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935989/
https://www.ncbi.nlm.nih.gov/pubmed/36800630
http://dx.doi.org/10.1097/MD.0000000000032966
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