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Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy

Vaginal microbiome is mutually beneficial to the host and has a significant impact on health and disease. Candida species, including Candida albicans, are part of the mucosal flora of most healthy women. Under suitable conditions, they can live in the vulvovaginal mucosa, resulting in symptomatic vu...

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Autores principales: Sun, Zhongwen, Ge, Xinnuo, Qiu, Bo, Xiang, Ze, Jiang, Chun, Wu, Jian, Li, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936092/
https://www.ncbi.nlm.nih.gov/pubmed/36816582
http://dx.doi.org/10.3389/fcimb.2023.1123026
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author Sun, Zhongwen
Ge, Xinnuo
Qiu, Bo
Xiang, Ze
Jiang, Chun
Wu, Jian
Li, Yuan
author_facet Sun, Zhongwen
Ge, Xinnuo
Qiu, Bo
Xiang, Ze
Jiang, Chun
Wu, Jian
Li, Yuan
author_sort Sun, Zhongwen
collection PubMed
description Vaginal microbiome is mutually beneficial to the host and has a significant impact on health and disease. Candida species, including Candida albicans, are part of the mucosal flora of most healthy women. Under suitable conditions, they can live in the vulvovaginal mucosa, resulting in symptomatic vulvovaginal candidiasis (VVC). Based on the analysis of 16S ribosomal RNA gene sequences, great progress has been made in exploring the composition and structure of vaginal bacterial community. Moreover, researchers have conducted several studies on whether vaginal microbiome will change during VVC infection. In addition, it has been reported that vaginal colonization of probiotics in vaginal microorganisms, especially Lactobacillus, can effectively reduce the risk of VVC and treat VVC. This review aims to summarize the changes of vaginal microflora during VVC infection, and further point out the possibility of using lactic acid bacteria as probiotics to treat VVC, so as to reduce the adverse consequences of VVC infection and reduce the expensive treatment cost.
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spelling pubmed-99360922023-02-18 Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy Sun, Zhongwen Ge, Xinnuo Qiu, Bo Xiang, Ze Jiang, Chun Wu, Jian Li, Yuan Front Cell Infect Microbiol Cellular and Infection Microbiology Vaginal microbiome is mutually beneficial to the host and has a significant impact on health and disease. Candida species, including Candida albicans, are part of the mucosal flora of most healthy women. Under suitable conditions, they can live in the vulvovaginal mucosa, resulting in symptomatic vulvovaginal candidiasis (VVC). Based on the analysis of 16S ribosomal RNA gene sequences, great progress has been made in exploring the composition and structure of vaginal bacterial community. Moreover, researchers have conducted several studies on whether vaginal microbiome will change during VVC infection. In addition, it has been reported that vaginal colonization of probiotics in vaginal microorganisms, especially Lactobacillus, can effectively reduce the risk of VVC and treat VVC. This review aims to summarize the changes of vaginal microflora during VVC infection, and further point out the possibility of using lactic acid bacteria as probiotics to treat VVC, so as to reduce the adverse consequences of VVC infection and reduce the expensive treatment cost. Frontiers Media S.A. 2023-02-03 /pmc/articles/PMC9936092/ /pubmed/36816582 http://dx.doi.org/10.3389/fcimb.2023.1123026 Text en Copyright © 2023 Sun, Ge, Qiu, Xiang, Jiang, Wu and Li https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Sun, Zhongwen
Ge, Xinnuo
Qiu, Bo
Xiang, Ze
Jiang, Chun
Wu, Jian
Li, Yuan
Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy
title Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy
title_full Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy
title_fullStr Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy
title_full_unstemmed Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy
title_short Vulvovaginal candidiasis and vaginal microflora interaction: Microflora changes and probiotic therapy
title_sort vulvovaginal candidiasis and vaginal microflora interaction: microflora changes and probiotic therapy
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936092/
https://www.ncbi.nlm.nih.gov/pubmed/36816582
http://dx.doi.org/10.3389/fcimb.2023.1123026
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