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Endo‐lysosomal protein concentrations in CSF from patients with frontotemporal dementia caused by CHMP2B mutation

INTRODUCTION: Increasing evidence implicates proteostatic dysfunction as an early event in the development of frontotemporal dementia (FTD). This study aimed to explore potential cerebrospinal fluid (CSF) biomarkers associated with the proteolytic systems in genetic FTD caused by CHMP2B mutation. ME...

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Detalles Bibliográficos
Autores principales: Toft, Anders, Sjödin, Simon, Simonsen, Anja Hviid, Ejlerskov, Patrick, Roos, Peter, Musaeus, Christian Sandøe, Henriksen, Emil Elbæk, Nielsen, Troels Tolstrup, Brinkmalm, Ann, Blennow, Kaj, Zetterberg, Henrik, Nielsen, Jørgen Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936136/
https://www.ncbi.nlm.nih.gov/pubmed/36815874
http://dx.doi.org/10.1002/dad2.12402