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Increased sensitivity to chemically induced colitis in mice harboring a DNA-binding deficient aryl hydrocarbon receptor
The aryl hydrocarbon receptor (AHR), a transcription factor best known for mediating toxic responses of environmental pollutants, also integrates metabolic signals to promote anti-inflammatory responses, intestinal homeostasis, and maintain barrier integrity. AHR regulates its target genes through d...
Autores principales: | Alvik, Karoline, Shao, Peng, Hutin, David, Baglole, Carolyn, Grant, Denis M, Matthews, Jason |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936212/ https://www.ncbi.nlm.nih.gov/pubmed/36519841 http://dx.doi.org/10.1093/toxsci/kfac132 |
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