Improved ventilatory response during exercise over time after concussion: A case report

This case study reports the exercise ventilatory responses of a 17‐year‐old female who sustained a traumatic brain injury (TBI) which resulted in loss of consciousness. Subsequently, she suffered from post‐concussion syndrome accompanied by orthostatic and exercise intolerance. A cardiopulmonary exercise test (CPET) was performed 2 years post‐TBI. The results demonstrated significant hypoventilation with elevated PetCO(2) and ventilatory equivalents, progressive desaturation, and pre‐syncope symptoms limiting exercise capacity. A repeat CPET 4 years post‐TBI demonstrated a similar exercise capacity limited by pre‐syncope symptoms. However, there was a marked improvement in the ventilatory response, with appropriate ventilation, PetCO(2), and ventilatory equivalents, and only minor desaturation near peak exercise. Hypoventilation during exercise has been reported in subjects with post‐concussion syndrome; however, with time the exercise ventilatory response can potentially normalize as observed in this subject.