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IL7 and IL7 Flt3L co-expressing CAR T cells improve therapeutic efficacy in mouse EGFRvIII heterogeneous glioblastoma

Chimeric antigen receptor (CAR) T cell therapy in glioblastoma faces many challenges including insufficient CAR T cell abundance and antigen-negative tumor cells evading targeting. Unfortunately, preclinical studies evaluating CAR T cells in glioblastoma focus on tumor models that express a single a...

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Detalles Bibliográficos
Autores principales:	Swan, Sheridan L., Mehta, Nalini, Ilich, Ekaterina, Shen, Steven H., Wilkinson, Daniel S., Anderson, Alexa R., Segura, Tatiana, Sanchez-Perez, Luis, Sampson, John H., Bellamkonda, Ravi V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936235/ https://www.ncbi.nlm.nih.gov/pubmed/36817432 http://dx.doi.org/10.3389/fimmu.2023.1085547

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