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Syngeneic model of carcinogen-induced tumor mimics basal/squamous, stromal-rich, and neuroendocrine molecular and immunological features of muscle-invasive bladder cancer

INTRODUCTION: Bladder cancer is a heterogenous disease and the emerging knowledge on molecular classification of bladder tumors may impact treatment decisions based on molecular subtype. Pre-clinical models representing each subtype are needed to test novel therapies. Carcinogen-induced bladder canc...

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Detalles Bibliográficos
Autores principales: Shah, Shruti D., Gillard, Bryan M., Wrobel, Michelle M., Karasik, Ellen, Moser, Michael T., Mastri, Michalis, Long, Mark D., Sule, Norbert, Brackett, Craig M., Huss, Wendy J., Foster, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936245/
https://www.ncbi.nlm.nih.gov/pubmed/36816919
http://dx.doi.org/10.3389/fonc.2023.1120329