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CBS-H(2)S axis preserves the intestinal barrier function by inhibiting COX-2 through sulfhydrating human antigen R in colitis

INTRODUCTION: Lipopolysaccharide (LPS) causes lesions of the epithelial barrier, which allows translocation of pathogens from the intestinal lumen to the host’s circulation. Hydrogen sulfide (H(2)S) regulates multiple physiological and pathological processes in colonic epithelial tissue, and CBS-H(2...

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Detalles Bibliográficos
Autores principales: Guo, Shihao, Huang, Zhihao, Zhu, Jing, Yue, Taohua, Wang, Xin, Pan, Yisheng, Bu, Dingfang, Liu, Yucun, Wang, Pengyuan, Chen, Shanwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936422/
https://www.ncbi.nlm.nih.gov/pubmed/36725190
http://dx.doi.org/10.1016/j.jare.2022.03.010

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