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Network-based modelling of mechano-inflammatory chondrocyte regulation in early osteoarthritis

Osteoarthritis (OA) is a debilitating joint disease characterized by articular cartilage degradation, inflammation and pain. An extensive range of in vivo and in vitro studies evidences that mechanical loads induce changes in chondrocyte gene expression, through a process known as mechanotransductio...

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Detalles Bibliográficos
Autores principales: Segarra-Queralt, Maria, Piella, Gemma, Noailly, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936426/
https://www.ncbi.nlm.nih.gov/pubmed/36815875
http://dx.doi.org/10.3389/fbioe.2023.1006066

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