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Network-based modelling of mechano-inflammatory chondrocyte regulation in early osteoarthritis
Osteoarthritis (OA) is a debilitating joint disease characterized by articular cartilage degradation, inflammation and pain. An extensive range of in vivo and in vitro studies evidences that mechanical loads induce changes in chondrocyte gene expression, through a process known as mechanotransductio...
Autores principales: | Segarra-Queralt, Maria, Piella, Gemma, Noailly, Jérôme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936426/ https://www.ncbi.nlm.nih.gov/pubmed/36815875 http://dx.doi.org/10.3389/fbioe.2023.1006066 |
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