Cargando…

P7C3-A20 Attenuates Microglial Inflammation and Brain Injury after ICH through Activating the NAD(+)/Sirt3 Pathway

Intracerebral hemorrhage (ICH) is lethal but lacks effective therapies. Nicotinamide adenine dinucleotide (NAD(+)) is a central metabolite indispensable for a broader range of fundamental intracellular biological functions. Reduction of NAD(+) usually occurs after acute brain insults, and supplement...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yang, Hu, Qing, Wu, Xun, Cai, Ya-ning, Zhang, Yun-ze, Wu, Ying-xi, Zhu, Gang, Luo, Jia-ning, Cheng, Hong-bo, Yu, Jie-gang, Wang, Xiao-liang, Gao, Li, Gao, Guo-dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936507/ https://www.ncbi.nlm.nih.gov/pubmed/36819779 http://dx.doi.org/10.1155/2023/7857760

Ejemplares similares

Resveratrol Attenuates Microglial Activation via SIRT1-SOCS1 Pathway
por: Zhang, Shuping, et al.
Publicado: (2017)

Wld(S) Reduces Paraquat-Induced Cytotoxicity via SIRT1 in Non-Neuronal Cells by Attenuating the Depletion of NAD
por: Yu, Qiujing, et al.
Publicado: (2011)

The NAD-dependent deacetylase SIRT2 regulates T cell differentiation involved in tumor immune response
por: Jiang, Cui, et al.
Publicado: (2020)

NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy
por: Qiu, Duojun, et al.
Publicado: (2022)

Hydrochloride fasudil attenuates brain injury in ICH rats
por: Li, Limin, et al.
Publicado: (2020)

The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD(+)/SIRT1 in mammalian aging and longevity control
por: Imai, Shin-ichiro
Publicado: (2016)

Activation of LRP6 with HLY78 Attenuates Oxidative Stress and Neuronal Apoptosis via GSK3β/Sirt1/PGC-1α Pathway after ICH
por: Jin, Peng, et al.
Publicado: (2022)

„Wenn ich groß bin, geh‘ ich in die Pflege“
por: Jerusalem, Anna, et al.
Publicado: (2022)

NAD(+) repletion attenuates obesity‐induced oocyte mitochondrial dysfunction and offspring metabolic abnormalities via a SIRT3‐dependent pathway
por: Yang, Qingling, et al.
Publicado: (2021)

Oxytocin inhibits lipopolysaccharide-induced inflammation in microglial cells and attenuates microglial activation in lipopolysaccharide-treated mice
por: Yuan, Lin, et al.
Publicado: (2016)

SIRT3, a Mitochondrial NAD(+)-Dependent Deacetylase, Is Involved in the Regulation of Myoblast Differentiation
por: Abdel Khalek, Waed, et al.
Publicado: (2014)

Nicotinamide mononucleotide attenuates HIF-1α activation and fibrosis in hypoxic adipose tissue via NAD(+)/SIRT1 axis
por: Wu, Keke, et al.
Publicado: (2023)

SIRT1-dependent restoration of NAD+ homeostasis after increased extracellular NAD+ exposure
por: Buonvicino, Daniela, et al.
Publicado: (2021)

NAD+ improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway
por: Wang, Jinli, et al.
Publicado: (2021)

Kampagne „ICH SEH, ICH SEH“ macht auf Diabetes aufmerksam
Publicado: (2020)

"Wehe, wenn ich erzähle, wehe, wenn ich nicht erzähle"
por: Zwipp,, Hans
Publicado: (2023)

Ich wíinikil : Intus decretum
por: Calderón Martín, Argelia Cuautlehuanitzin
Publicado: (2012)

Was ich sagen wollte /
por: Radecki, Sigismund von

EGCG treats ICH via up-regulating miR-137-3p and inhibiting Parthanatos
por: Wang, Jianjun, et al.
Publicado: (2020)

The Role of NAD+, SIRTs Interactions in Stimulating and Counteracting Carcinogenesis
por: Podyacheva, Ekaterina, et al.
Publicado: (2023)

Tumor growth of neurofibromin-deficient cells is driven by decreased respiration and hampered by NAD(+) and SIRT3
por: Masgras, Ionica, et al.
Publicado: (2022)

DHEA Attenuates Microglial Activation via Induction of JMJD3 in Experimental Subarachnoid Haemorrhage
por: Tao, Tao, et al.
Publicado: (2019)

SIRT1 activation by minocycline on regulation of microglial polarization homeostasis
por: Wu, Ling-Hsuan, et al.
Publicado: (2020)

Nicotinamide Mononucleotide Supplementation Improves Mitochondrial Dysfunction and Rescues Cellular Senescence by NAD(+)/Sirt3 Pathway in Mesenchymal Stem Cells
por: Wang, Huan, et al.
Publicado: (2022)

Microglial activating transcription factor 3 upregulation: An indirect target to attenuate inflammation in the nervous system
por: Holland, Seth D., et al.
Publicado: (2023)

Paeonol attenuates inflammation-mediated neurotoxicity and microglial activation
por: Nam, Kyong Nyon, et al.
Publicado: (2013)

"Als Controller weiß ich oft mehr, als ich selbst kommunizieren darf"
por: Schäffer, Utz
Publicado: (2021)

Nicotinamide ameliorates mitochondria-related neuronal apoptosis and cognitive impairment via the NAD(+)/SIRT3 pathway
por: Hao, Keke, et al.
Publicado: (2023)

AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis
por: Ma, Chunmei, et al.
Publicado: (2021)

CD38-NAD(+)-Sirt1 axis in T cell immunotherapy
por: Chatterjee, Shilpak, et al.
Publicado: (2019)

Ich wíinikil-Intus decretum
por: Riveros Elox, José Ricardo
Publicado: (2012)

"Ich bin keine boss"
por: Cerutti, H
Publicado: (1992)

Bitte, was habe ich davon?
Publicado: (2008)

Natürlich habe ich Träume
Publicado: (2008)

Revision of ICH S8 Needed?
por: Van Der Laan, Jan Willem
Publicado: (2022)

Sirtuin 3 Dependent and Independent Effects of NAD(+) to Suppress Vascular Inflammation and Improve Endothelial Function in Mice
por: Cao, Xiaoyun, et al.
Publicado: (2022)

24-Hour ICH Score Is a Better Predictor of Outcome than Admission ICH Score
por: Aysenne, Aimee M., et al.
Publicado: (2013)

Total Burden of Cerebral Small Vessel Disease in Recurrent ICH versus First-ever ICH
por: Xu, Mangmang, et al.
Publicado: (2019)

NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1
por: Aguilar-Arnal, Lorena, et al.
Publicado: (2015)

Pterostilbene attenuates microglial inflammation and brain injury after intracerebral hemorrhage in an OPA1-dependent manner
por: Wu, Yang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bqtqnncmtk0ls889mb9acqbsc5