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Metasurface-Enabled 3-in-1 Microscopy
[Image: see text] Edge enhancement and polarization detection are critical to image transparent or low-contrast samples. However, currently available systems are limited to performing only a single functionality. To meet the requirement of system integration, there is a pressing need for a microscop...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936625/ https://www.ncbi.nlm.nih.gov/pubmed/36820325 http://dx.doi.org/10.1021/acsphotonics.2c01971 |
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author | Intaravanne, Yuttana Ansari, Muhammad Afnan Ahmed, Hammad Bileckaja, Narina Yin, Huabing Chen, Xianzhong |
author_facet | Intaravanne, Yuttana Ansari, Muhammad Afnan Ahmed, Hammad Bileckaja, Narina Yin, Huabing Chen, Xianzhong |
author_sort | Intaravanne, Yuttana |
collection | PubMed |
description | [Image: see text] Edge enhancement and polarization detection are critical to image transparent or low-contrast samples. However, currently available systems are limited to performing only a single functionality. To meet the requirement of system integration, there is a pressing need for a microscope with multiple functionalities. Here, we propose and develop a microscope with three different functionalities based on spatial multiplexing and polarization splitting. A novel geometric metasurface (MS) is used to realize a spiral phase profile and two phase gradient profiles along two vertical directions, which can perform such an extremely challenging optical task. This is the first demonstration of a 3-in-1 microscope that can simultaneously obtain five images with different optical properties in an imaging plane for the same sample. Imaging experiments with different samples verify its capability to simultaneously perform edge imaging, polarimetric imaging, and conventional microscope imaging. Benefiting from the compactness and multifunctionality of the optical MS device, the integration does not increase the volume of the microscope. This approach can enable users to visualize the multiple facets of samples in real-time. |
format | Online Article Text |
id | pubmed-9936625 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-99366252023-02-18 Metasurface-Enabled 3-in-1 Microscopy Intaravanne, Yuttana Ansari, Muhammad Afnan Ahmed, Hammad Bileckaja, Narina Yin, Huabing Chen, Xianzhong ACS Photonics [Image: see text] Edge enhancement and polarization detection are critical to image transparent or low-contrast samples. However, currently available systems are limited to performing only a single functionality. To meet the requirement of system integration, there is a pressing need for a microscope with multiple functionalities. Here, we propose and develop a microscope with three different functionalities based on spatial multiplexing and polarization splitting. A novel geometric metasurface (MS) is used to realize a spiral phase profile and two phase gradient profiles along two vertical directions, which can perform such an extremely challenging optical task. This is the first demonstration of a 3-in-1 microscope that can simultaneously obtain five images with different optical properties in an imaging plane for the same sample. Imaging experiments with different samples verify its capability to simultaneously perform edge imaging, polarimetric imaging, and conventional microscope imaging. Benefiting from the compactness and multifunctionality of the optical MS device, the integration does not increase the volume of the microscope. This approach can enable users to visualize the multiple facets of samples in real-time. American Chemical Society 2023-01-26 /pmc/articles/PMC9936625/ /pubmed/36820325 http://dx.doi.org/10.1021/acsphotonics.2c01971 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Intaravanne, Yuttana Ansari, Muhammad Afnan Ahmed, Hammad Bileckaja, Narina Yin, Huabing Chen, Xianzhong Metasurface-Enabled 3-in-1 Microscopy |
title | Metasurface-Enabled
3-in-1 Microscopy |
title_full | Metasurface-Enabled
3-in-1 Microscopy |
title_fullStr | Metasurface-Enabled
3-in-1 Microscopy |
title_full_unstemmed | Metasurface-Enabled
3-in-1 Microscopy |
title_short | Metasurface-Enabled
3-in-1 Microscopy |
title_sort | metasurface-enabled
3-in-1 microscopy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936625/ https://www.ncbi.nlm.nih.gov/pubmed/36820325 http://dx.doi.org/10.1021/acsphotonics.2c01971 |
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