Identification of anti-citrullinated osteopontin antibodies and increased inflammatory response by enhancement of osteopontin binding to fibroblast-like synoviocytes in rheumatoid arthritis

BACKGROUND: Anti-citrullinated protein/peptide antibodies (ACPAs) are present in patients at onset and have important pathogenic roles during the course of rheumatoid arthritis (RA). The characteristics of several molecules recognized by ACPA have been studied in RA, but the positivity rate of autoa...

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Detalles Bibliográficos
Autores principales: Umemoto, Akio, Kuwada, Takeshi, Murata, Koichi, Shiokawa, Masahiro, Ota, Sakiko, Murotani, Yoshiki, Itamoto, Akihiro, Nishitani, Kohei, Yoshitomi, Hiroyuki, Fujii, Takayuki, Onishi, Akira, Onizawa, Hideo, Murakami, Kosaku, Tanaka, Masao, Ito, Hiromu, Seno, Hiroshi, Morinobu, Akio, Matsuda, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936655/
https://www.ncbi.nlm.nih.gov/pubmed/36804906
http://dx.doi.org/10.1186/s13075-023-03007-9

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