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Targeting tumor exosomal circular RNA cSERPINE2 suppresses breast cancer progression by modulating MALT1-NF-𝜅B-IL-6 axis of tumor-associated macrophages

BACKGROUND: Circular RNAs (circRNAs) have important regulatory functions in cancer, but the role of circRNAs in the tumor microenvironment (TME) remains unclear. Moreover, we also explore the effects of si-circRNAs loaded in nanoparticles as therapeutic agent for anti-tumor in vivo. METHODS: We cond...

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Detalles Bibliográficos
Autores principales: Zhou, Boxuan, Mo, Zhaohong, Lai, Guie, Chen, Xiaohong, Li, Ruixi, Wu, Runxin, Zhu, Jia, Zheng, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936722/
https://www.ncbi.nlm.nih.gov/pubmed/36797769
http://dx.doi.org/10.1186/s13046-023-02620-5

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