Cargando…
Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome
BACKGROUND: Exfoliation syndrome (XFS) is an age-related systemic disorder characterized by excessive production and progressive accumulation of abnormal extracellular material, with pathognomonic ocular manifestations. It is the most common cause of secondary glaucoma, resulting in widespread globa...
Autores principales: | Hirbo, Jibril B., Pasutto, Francesca, Gamazon, Eric R., Evans, Patrick, Pawar, Priyanka, Berner, Daniel, Sealock, Julia, Tao, Ran, Straub, Peter S., Konkashbaev, Anuar I., Breyer, Max A., Schlötzer-Schrehardt, Ursula, Reis, André, Brantley, Milam A., Khor, Chiea C., Joos, Karen M., Cox, Nancy J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936777/ https://www.ncbi.nlm.nih.gov/pubmed/36797672 http://dx.doi.org/10.1186/s12864-023-09179-7 |
Ejemplares similares
-
Genetics and Genomics of Pseudoexfoliation Syndrome/Glaucoma
por: Schlötzer-Schrehardt, Ursula
Publicado: (2011) -
Pseudoexfoliation Syndrome: The Puzzle Continues
por: Schlötzer-Schrehardt, Ursula
Publicado: (2012) -
Evidence of selection on splicing-associated loci in human populations and relevance to disease loci mapping
por: Gamazon, Eric R., et al.
Publicado: (2017) -
Dysregulated Retinoic Acid Signaling in the Pathogenesis of Pseudoexfoliation Syndrome
por: Zenkel, Matthias, et al.
Publicado: (2022) -
Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1
por: Pasutto, Francesca, et al.
Publicado: (2017)