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Panax notoginseng saponins (PNS) attenuate Th17 cell differentiation in CIA mice via inhibition of nuclear PKM2-mediated STAT3 phosphorylation

CONTEXT: Rheumatoid arthritis (RA) is an autoimmune disease with aberrant Th17 cell differentiation. Panax notoginseng (Burk.) F. H. Chen (Araliaceae) saponins (PNS) have an anti-inflammatory effect and can suppress Th17 cell differentiation. OBJECTIVE: To investigate mechanisms of PNS on Th17 cell...

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Detalles Bibliográficos
Autores principales:	Shen, Mei-Yu, Di, Yu-Xi, Wang, Xiang, Tian, Feng-Xiang, Zhang, Ming-Fei, Qian, Fei-Ya, Jiang, Bao-Ping, Zhou, Xue-Ping, Zhou, Ling-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936999/ https://www.ncbi.nlm.nih.gov/pubmed/36794740 http://dx.doi.org/10.1080/13880209.2023.2173248

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