Coronavirus RNA-dependent RNA polymerase interacts with the p50 regulatory subunit of host DNA polymerase delta and plays a synergistic role with RNA helicase in the induction of DNA damage response and cell cycle arrest in the S phase

Disruption of the cell cycle is a common strategy shared by many viruses to create a conducible cellular microenvironment for their efficient replication. We have previously shown that infection of cells with gammacoronavirus infectious bronchitis virus (IBV) activated the theataxia-telangiectasia m...

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Detalles Bibliográficos
Autores principales: Quan, Li, Sun, Xinxin, Xu, Linghui, Chen, Rui Ai, Liu, Ding Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Coronaviruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937006/
https://www.ncbi.nlm.nih.gov/pubmed/36724449
http://dx.doi.org/10.1080/22221751.2023.2176008

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