Stage of infection with Mycobacterium avium subsp. paratuberculosis impacts expression of Rab5, Rab7, and CYP27B1 in macrophages within the ileum of naturally infected cows

INTRODUCTION: Macrophages are the preferential target of Mycobacterium avium subsp. paratuberculosis (MAP), the etiologic agent of ruminant paratuberculosis. Uptake of pathogens by intestinal macrophages results in their trafficking through endosomal compartments, ultimately leading to fusion with a...

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Detalles Bibliográficos
Autores principales: Wherry, Taylor L. T., Heggen, Mark, Shircliff, Adrienne L., Mooyottu, Shankumar, Stabel, Judith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937430/
https://www.ncbi.nlm.nih.gov/pubmed/36816182
http://dx.doi.org/10.3389/fvets.2023.1117591

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