Rad51 filaments assembled in the absence of the complex formed by the Rad51 paralogs Rad55 and Rad57 are outcompeted by translesion DNA polymerases on UV-induced ssDNA gaps

The bypass of DNA lesions that block replicative polymerases during DNA replication relies on DNA damage tolerance pathways. The error-prone translesion synthesis (TLS) pathway depends on specialized DNA polymerases that incorporate nucleotides in front of base lesions, potentially inducing mutagene...

Descripción completa

Detalles Bibliográficos
Autores principales: Maloisel, Laurent, Ma, Emilie, Phipps, Jamie, Deshayes, Alice, Mattarocci, Stefano, Marcand, Stéphane, Dubrana, Karine, Coïc, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937489/
https://www.ncbi.nlm.nih.gov/pubmed/36749784
http://dx.doi.org/10.1371/journal.pgen.1010639

Ejemplares similares

Ejemplares similares