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Broad protective vaccination against systemic Escherichia coli with autotransporter antigens
Extraintestinal pathogenic Escherichia coli (ExPEC) is the leading cause of adult life-threatening sepsis and urinary tract infections (UTI). The emergence and spread of multidrug-resistant (MDR) ExPEC strains result in a considerable amount of treatment failure and hospitalization costs, and contri...
Autores principales: | Xing, Yikun, Clark, Justin R., Chang, James D., Chirman, Dylan M., Green, Sabrina, Zulk, Jacob J., Jelinski, Joseph, Patras, Kathryn A., Maresso, Anthony W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937491/ https://www.ncbi.nlm.nih.gov/pubmed/36800400 http://dx.doi.org/10.1371/journal.ppat.1011082 |
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