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Initial spindle positioning at the oocyte center protects against incorrect kinetochore-microtubule attachment and aneuploidy in mice
Spindle positioning within the oocyte must be tightly regulated. In mice, the spindle is predominantly assembled at the oocyte center before its migration toward the cortex to achieve the highly asymmetric division, a characteristic of female meiosis. The significance of the initial central position...
Autores principales: | Kincade, Jessica N., Hlavacek, Avery, Akera, Takashi, Balboula, Ahmed Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937575/ https://www.ncbi.nlm.nih.gov/pubmed/36800430 http://dx.doi.org/10.1126/sciadv.add7397 |
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