Cargando…

Efficacy and safety of metabolic interventions for the treatment of severe COVID-19: in vitro, observational, and non-randomized open-label interventional study

BACKGROUND: Viral infection is associated with a significant rewire of the host metabolic pathways, presenting attractive metabolic targets for intervention. METHODS: We chart the metabolic response of lung epithelial cells to SARS-CoV-2 infection in primary cultures and COVID-19 patient samples and...

Descripción completa

Detalles Bibliográficos
Autores principales: Ehrlich, Avner, Ioannidis, Konstantinos, Nasar, Makram, Abu Alkian, Ismaeel, Daskal, Yuval, Atari, Nofar, Kliker, Limor, Rainy, Nir, Hofree, Matan, Shafran Tikva, Sigal, Houri, Inbal, Cicero, Arrigo, Pavanello, Chiara, Sirtori, Cesare R, Cohen, Jordana B, Chirinos, Julio A, Deutsch, Lisa, Cohen, Merav, Gottlieb, Amichai, Bar-Chaim, Adina, Shibolet, Oren, Mandelboim, Michal, Maayan, Shlomo L, Nahmias, Yaakov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937660/
https://www.ncbi.nlm.nih.gov/pubmed/36705566
http://dx.doi.org/10.7554/eLife.79946