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Efficacy and safety of metabolic interventions for the treatment of severe COVID-19: in vitro, observational, and non-randomized open-label interventional study
BACKGROUND: Viral infection is associated with a significant rewire of the host metabolic pathways, presenting attractive metabolic targets for intervention. METHODS: We chart the metabolic response of lung epithelial cells to SARS-CoV-2 infection in primary cultures and COVID-19 patient samples and...
Autores principales: | Ehrlich, Avner, Ioannidis, Konstantinos, Nasar, Makram, Abu Alkian, Ismaeel, Daskal, Yuval, Atari, Nofar, Kliker, Limor, Rainy, Nir, Hofree, Matan, Shafran Tikva, Sigal, Houri, Inbal, Cicero, Arrigo, Pavanello, Chiara, Sirtori, Cesare R, Cohen, Jordana B, Chirinos, Julio A, Deutsch, Lisa, Cohen, Merav, Gottlieb, Amichai, Bar-Chaim, Adina, Shibolet, Oren, Mandelboim, Michal, Maayan, Shlomo L, Nahmias, Yaakov |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937660/ https://www.ncbi.nlm.nih.gov/pubmed/36705566 http://dx.doi.org/10.7554/eLife.79946 |
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