JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation

It is an effective strategy to treat tuberculosis by enhancing reactive oxygen species- (ROS-) mediated killing of Mycobacterium tuberculosis in macrophages, but there are no current therapeutic agents targeting this pathway. Honeysuckle has been used as the traditional medicine for tuberculosis tre...

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Detalles Bibliográficos
Autores principales: Wan, Haoqiang, Cai, Yi, Xiao, Lingyun, Ling, Yunzhi, Ge, Lanlan, Mo, Siwei, Xie, Qiujie, Peng, Shusong, Zhou, Boping, Zeng, Xiaobin, Chen, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937762/
https://www.ncbi.nlm.nih.gov/pubmed/36819778
http://dx.doi.org/10.1155/2023/6726654

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