Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn(2+) coordination and substrate binding

Members of glycosyltransferase family 75 (GT75) not only reversibly catalyze the autoglycosylation of a conserved arginine residue with specific NDP-sugars but also exhibit NDP-pyranose mutase activity that reversibly converts specific NDP-pyranose to NDP-furanose. The latter activity provides valua...

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Detalles Bibliográficos
Autores principales: Du, Xueqing, Chu, Xuan, Liu, Ning, Jia, Xiaoyu, Peng, Hui, Xiao, Yazhong, Liu, Lin, Yu, Haizhu, Li, Fudong, He, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937993/
https://www.ncbi.nlm.nih.gov/pubmed/36642179
http://dx.doi.org/10.1016/j.jbc.2023.102903

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