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Circadian disruption alters gut barrier integrity via a ß-catenin-MMP-related pathway
We evaluated the mechanistic link between circadian rhythms and gut barrier permeability. Mice were subjected to either constant 24-h light (LL) or 12-h light/dark cycles (LD). Mice housed in LL experienced a significant increase in gut barrier permeability that was associated with dysregulated ß-ca...
Autores principales: | Eum, Sung Yong, Schurhoff, Nicolette, Teglas, Timea, Wolff, Gretchen, Toborek, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938043/ https://www.ncbi.nlm.nih.gov/pubmed/35976519 http://dx.doi.org/10.1007/s11010-022-04536-8 |
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