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A proof of concept reinforcement learning based tool for non parametric population pharmacokinetics workflow optimization

The building of population pharmacokinetic models can be described as an iterative process in which given a model and a dataset, the pharmacometrician introduces some changes to the model specification, then perform an evaluation and based on the predictions obtained performs further optimization. T...

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Detalles Bibliográficos
Autores principales: Otalvaro, J. D., Yamada, W. M., Hernandez, A. M., Zuluaga, A. F., Chen, R., Neely, M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938066/
https://www.ncbi.nlm.nih.gov/pubmed/36478350
http://dx.doi.org/10.1007/s10928-022-09829-5