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Xanomeline restores endogenous nicotinic acetylcholine receptor signaling in mouse prefrontal cortex
Cholinergic synapses in prefrontal cortex are vital for attention, but this modulatory system undergoes substantial pre- and post-synaptic alterations during adulthood. To examine the integrated impact of these changes, we optophysiologically probe cholinergic synapses ex vivo, revealing a clear dec...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938126/ https://www.ncbi.nlm.nih.gov/pubmed/36635596 http://dx.doi.org/10.1038/s41386-023-01531-5 |