PLK1 inhibition promotes apoptosis and DNA damage in glioma stem cells by regulating the nuclear translocation of YBX1

Glioma stem cells (GSCs) are the important cause of tumorigenesis, recurrence, and chemo(radio)resistance in glioma. Targeting GSCs helps improve the outcomes of glioma treatment. Polo-like kinase 1 (PLK1) is a member of the serine/threonine protein kinase family, which is highly conserved. In recen...

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Detalles Bibliográficos
Autores principales: Li, Xuetao, Chen, Guangliang, Liu, Bin, Tao, Zhennan, Wu, Yue, Zhang, Kai, Feng, Zibin, Huang, Yulun, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938146/
https://www.ncbi.nlm.nih.gov/pubmed/36805592
http://dx.doi.org/10.1038/s41420-023-01302-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938146/
https://www.ncbi.nlm.nih.gov/pubmed/36805592
http://dx.doi.org/10.1038/s41420-023-01302-7

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