Generating in vitro models of NTRK-fusion mesenchymal neoplasia as tools for investigating kinase oncogenic activation and response to targeted therapy

The discovery of neurotrophic tyrosine receptor kinase (NTRK) gene fusions as pan-tumor oncogenic drivers has led to new personalized therapies in oncology. Recent studies investigating NTRK fusions among mesenchymal neoplasms have identified several emerging soft tissue tumor entities displaying va...

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Detalles Bibliográficos
Autores principales: Vanoli, Fabio, Herviou, Laurie, Tsuda, Yusuke, Sung, Patricia, Xie, Ziyu, Fishinevich, Eve, Min, Soe S., Mallen, William, de Wardin, Henry de Traux, Zhang, Yanming, Jasin, Maria, Antonescu, Cristina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938185/
https://www.ncbi.nlm.nih.gov/pubmed/36801905
http://dx.doi.org/10.1038/s41389-023-00454-6

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