Koller and the dawn of cancer cytogenetics

Shortly before the DNA era began, PC Koller described lagging chromosomes and chromosome numerical abnormalities in human carcinomas. While present-day cancer geneticists would question some of Koller’s conclusions, this study ultimately contributed to the realisation that chromosomal instability is...

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Autor principal: Norbury, Chris J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938233/
https://www.ncbi.nlm.nih.gov/pubmed/36229580
http://dx.doi.org/10.1038/s41416-022-01996-z
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author Norbury, Chris J.
author_facet Norbury, Chris J.
author_sort Norbury, Chris J.
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description Shortly before the DNA era began, PC Koller described lagging chromosomes and chromosome numerical abnormalities in human carcinomas. While present-day cancer geneticists would question some of Koller’s conclusions, this study ultimately contributed to the realisation that chromosomal instability is a widespread feature of solid tumours.
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spelling pubmed-99382332023-02-19 Koller and the dawn of cancer cytogenetics Norbury, Chris J. Br J Cancer Comment Shortly before the DNA era began, PC Koller described lagging chromosomes and chromosome numerical abnormalities in human carcinomas. While present-day cancer geneticists would question some of Koller’s conclusions, this study ultimately contributed to the realisation that chromosomal instability is a widespread feature of solid tumours. Nature Publishing Group UK 2022-10-13 2023-02-02 /pmc/articles/PMC9938233/ /pubmed/36229580 http://dx.doi.org/10.1038/s41416-022-01996-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Norbury, Chris J.
Koller and the dawn of cancer cytogenetics
title Koller and the dawn of cancer cytogenetics
title_full Koller and the dawn of cancer cytogenetics
title_fullStr Koller and the dawn of cancer cytogenetics
title_full_unstemmed Koller and the dawn of cancer cytogenetics
title_short Koller and the dawn of cancer cytogenetics
title_sort koller and the dawn of cancer cytogenetics
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938233/
https://www.ncbi.nlm.nih.gov/pubmed/36229580
http://dx.doi.org/10.1038/s41416-022-01996-z
work_keys_str_mv AT norburychrisj kollerandthedawnofcancercytogenetics

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